Sep 04, 2020 · A systematic review of cases of local anesthetic-related methemoglobinemia found that benzocaine was an agent in two-thirds of cases. This higher association with benzocaine-containing products has led the United States Food and Drug Administration to release multiple advisories regarding the use of benzocaine-containing oral products. Methemoglobinemia Differential DiagnosesDec 21, 2020 · Cyanosis (presence of more than 5 g/dL of deoxygenated hemoglobin) associated with hypoxia may be caused by cardiac or pulmonary disease. Cyanosis may also be present in polycythemia but is generally without hypoxia. The hallmark of methemoglobinemia is cyanosis that is unresponsive to high oxygen concentrations in the absence of cardiac or pulmonary disorders.
Methemoglobinemia Related To Local Anesthetics:A Summary Of 242 Episodes 2:41; Safety And Driving Ability Following Low-dose Propofol Sedation 1:12; Assessment Of Short-term Outcomes Following Unintentional Ingestions Of "Oral Contraceptive Pills 26s; Primary Care Physicians' Use Of An Electronic Medical Record System:A Cognitive Task Analysis 1:57 Methemoglobinemia Related to Local Anesthetics:A Aug 11, 2012 · Overview. This article was chosen for discussion as the use of local anesthetics is quite prevalent and as anesthesiologist, we need to be aware of the implications of our treatment and their adverse effectsThis article is a great review of literature on methemoglobinemia and LAs Methemoglobinemia:Practice Essentials, Background Dec 21, 2020 · Practice Essentials Methemoglobinemia (congenital or acquired) occurs when red blood cells (RBCs) contain methemoglobin at levels higher than 1%. Methemoglobin results from the presence of iron in
The formation of methemoglobinemia following use of npropylamino2methylpropionanilide (L67) was measured both in a clinical study and in animal experiments. In the study of 60 patients receiving doses of 400 to 1,200 mg, 62% developed measureable amounts of methemoglobin. The highest value found represented 18% of the total hemoglobin. Rapid reconversion to the normal pigment by Neonatal Pain Management - ScienceDirectSep 01, 1992 · Holve RI:Regional anesthesia during newborn circumcision. Clin Pediatr 22:812-818, 1983 48. Jacobsen S, Koren G:New approaches to topical anesthesia in children. Curr Opin Pediatr 2:234-237, 1990 49. Jakobson B, Nilson A:Methemoglobinemia associated with a prilocaine-lidocaine cream and tri- methoprim-sulfamethozole:A case report. The influence of lidocaine topical anesthesia during Feb 07, 2015 · Four types of local anesthetics have been suspected as possible cause of methemoglobinemia:prilocaine, benzocaine, lidocaine, and tetracaine. Its occurrence may be possibly related to a number of clinical factors such as age, dose of medication, enzyme deficiencies, malnutrition, mucosal erosion, hospitalization, sepsis, and anemia [ 7 ].
Jun 01, 2020 · Methemoglobinemia (congenital or acquired) occurs when red blood cells (RBCs) contain methemoglobin at levels higher than 1%. Methemoglobin results Methemoglobinemia related to local anesthetics:a summary The purpose of this article is to summarize all episodes of local anesthetic-related methemoglobinemia found in the medical literature. METHODS I performed a search of the American National Library of Medicine's PubMed with the following key words:"local anesthetic" and "methemoglobinemia."